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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/175809
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- Title
- Standard guidelines for the chromosome-centric human proteome project
- Related
- Journal of proteome research, Vol. 11, No. 4, (2012), p.2005-2013
- DOI
- 10.1021/pr200824a
- Publisher
- American Chemical Society
- Date
- 2012
- Author/Creator
- Paik, Young-Ki
- Author/Creator
- Omenn, Gilbert S
- Author/Creator
- Na, Ketun
- Author/Creator
- Jeong, Seul-Ki
- Author/Creator
- He, Fuchu
- Author/Creator
- Binz, Pierre-Alain
- Author/Creator
- Nishimura, Toshihide
- Author/Creator
- Keown, Paul
- Author/Creator
- Baker, Mark S
- Author/Creator
- Yoo, Jong Shin
- Author/Creator
- Garin, Jerome
- Author/Creator
- Archakov, Alexander
- Author/Creator
- Uhlen, Mathias
- Author/Creator
- Bergeron, John
- Author/Creator
- Salekdeh, Ghasem Hosseini
- Author/Creator
- Hancock, William S
- Author/Creator
- Hanash, Samir
- Author/Creator
- Marko-Varga, György
- Author/Creator
- Aebersold, Ruedi
- Author/Creator
- Bairoch, Amos
- Author/Creator
- Yamamoto, Tadashi
- Author/Creator
- Legrain, Pierre
- Author/Creator
- Lee, Hyoung-Joo
- Description
- The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-HPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard guidelines to manage these international efforts more efficiently by mobilizing existing resources and collaborative networks. The C-HPP guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits. A companion approach for the Biology and Disease-Driven HPP (B/D-HPP) component of the Human Proteome Project is currently being organized, building upon the Human Proteome Organization's organ-based and biofluid-based initiatives (www.hupo.org/research). The common application of these guidelines in the participating laboratories is expected to facilitate the goal of a comprehensive analysis of the human proteome.
- Description
- 9 page(s)
- Subject Keyword
- 060100 Biochemistry and Cell Biology
- Subject Keyword
- antibody
- Subject Keyword
- Biology/Disease-Driven Human Proteome Project
- Subject Keyword
- Chromosome-Centric Human Proteome Project
- Subject Keyword
- Human Genome Project
- Subject Keyword
- Human Proteome Organization
- Subject Keyword
- Human Proteome Project
- Subject Keyword
- knowledge-base
- Subject Keyword
- mass spectrometry
- Resource Type
- journal article
- Organisation
- Macquarie University. Department of Chemistry and Biomolecular Sciences
- Identifier
- http://hdl.handle.net/1959.14/175809
- Identifier
- mq:20175
- Identifier
- ISSN:1535-3893
- Identifier
- mq-rm-2011007210
- Identifier
- mq_res-ext-2-s2.0-84859622404
- Language
- eng
- Reviewed
Macquarie University ResearchOnline
