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colorectal cancer

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Add  Characterization of the interaction between heterodimeric αvβ6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics
Authors: Ahn, Seong Beom | Mohamedali, Abidali | Agrez, Michael | Nice, Edouard C | Baker, Mark S | Anand, Samyuktha | Cheruku, Harish R | Birch, Debra | Gopichandran, Sowmya | Cantor, David | Ranganathan, Shoba | Inglis, David W | Frank, Ronald
Date: 2014
Subject Keyword: colorectal cancer | functional proteomics | ovarian cancer | peptide array | proximity ligation assay | uPAR | αvβ6 integrin
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/325450
Description: Urokinase plasminogen activator receptor (uPAR) and the epithelial integrin αvβ6 are thought to individually play critical roles in cancer metastasis. These observations have been highlighted by the r ... More
Reviewed: Reviewed
Add  Comparative N-glycan profiling of colorectal cancer cell lines reveals unique bisecting GlcNAc and α-2,3-linked sialic acid determinants are associated with membrane proteins of the more metastatic/aggressive cell lines
Authors: Sethi, Manveen K | Thaysen-Andersen, Morten | Smith, Joshua T | Baker, Mark S | Packer, Nicolle H | Hancock, William S | Fanayan, Susan
Date: 2014
Subject Keyword: bisecting GlcNAc | colorectal cancer | fucosylation | high mannose | mass spectrometry | membrane proteins | N- glycosylation | sialylation
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/301157
Description: Advances in colorectal cancer (CRC) diagnosis will be enhanced by development of more sensitive and reliable methods for early detection of the disease when treatment is more effective. Because many k ... More
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Add  Overexpression of αvβ6 integrin alters the colorectal cancer cell proteome in favor of elevated proliferation and a switching in cellular adhesion that increases invasion
Authors: Cantor, David | Slapetova, Iveta | Kan, Alison | McQuade, Leon R | Baker, Mark S
Date: 2013
Subject Keyword: 060100 Biochemistry and Cell Biology | β6 Integrins | colorectal cancer | epithelial-mesenchymal transition | metastasis | membrane proteomics
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/287697
Description: Many proteins enhance cancer progression toward life-threatening metastases. These include linking proteins called integrins that mediate cell adhesion to the extracellular matrix (ECM), consequently ... More
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Add  The Development of multiple reaction monitoring assays for liver-derived plasma proteins
Authors: Mckay, Matthew J | Sherman, Jamie | Laver, Matthew T | Baker, Mark S | Clarke, Stephen J | Molloy, Mark P
Date: 2007
Subject Keyword: 110100 Medical Biochemistry and Metabolomics | biomarker | colorectal cancer | Multiple reaction monitoring (MRM) | quantitation | tandem mass spectrometry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/42140
Description: There is wide interpatient variability in toxicity to chemotherapeutic drugs and a lack of routine clinical tests for prospectively identifying patients at risk of developing toxicity from chemotherap ... More
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