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Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1029537
Description: Pericapsular fibrotic overgrowth (PFO) is associated with poor survival of encapsulated pancreatic islets. Modification of the microcapsule membrane aimed at preventing PFO should improve graft surviv ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/223552
Description: Encapsulation of human islets may prevent their immune rejection when transplanted into diabetic recipients. To assist in understanding why clinical outcomes with encapsulated islets were not ideal, w ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/223549
Description: Pericapsular fibrotic overgrowth (PFO) may be attributed to an immune response against microcapsules themselves or to antigen shedding through microcapsule pores from encapsulated islet tissue. Modifi ... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/223087
Description: Despite encouraging results in animal models, the transplantation of microencapsulated islets into humans has yet to make a therapeutic impact. Recent clinical trials using microencapsulated human isl ... More
Reviewed: Reviewed
Date: 2003
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.14/16410
Description: As a xenotransplant, foetal pig islet-like cell clusters (ICCs) are tissues with a potential to reverse hyperglycaemia in Type I diabetes. Following the exposure of ICCs to some pro-inflammatory cytok ... More
Reviewed: Reviewed
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